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Creating "digital embryos" means mapping the behavior of all cells during embryogenesis -- a long-standing goal of biology. To achieve this goal, Keller et al. developed a new type of microscopy with a "plane of light" that rapidly moves a micrometer-thin beam of laser light vertically and horizontally through the specimen. With it, the team recorded nuclei localization and movement of about 92% of all cells in entire zebrafish embryos (video) over the first 24 hours of development.