• Video contributions from authors of Science papers

Modeling a Pandemic

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In 2009, H1N1 became the first influenza pandemic of the 21st century, and prompted swift investigation of ways to control the virus. Vaccination can slow the flu's spread and reduce its attack rate and mortality, but the strategy's effectiveness depends on who gets the vaccine, and when. Yang et al. used household and school studies to model the effectiveness of two vaccination strategies on the spread of H1N1. They report that a 70% phased vaccination program in which the vaccine is universally available (first movie clip) is not as effective as a similar vaccination program in which children are vaccinated first, followed by adults (second clip).

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